人类

IKZF3 - IKAROS Family Zinc Finger 3

Alias:
AIO
IMD84
AIOLOS
ZNFN1A3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码Ikaros锌指蛋白家族的一员。这个蛋白质家族的三个成员(Ikaros、Aiolos和Helios)是参与调节淋巴细胞发育的造血特异性转录因子。这个基因产物是一种转录因子,在调节B淋巴细胞增殖和分化中起着重要作用。Ikaros和Aiolos都可以参与染色质重塑。Aiolos在B淋巴细胞中的基因表达调节是复杂的,因为它似乎需要依次形成Ikaros同源二聚体、Ikaros/Aiolos异源二聚体和Aiolos同源二聚体。已经描述了几个编码不同异构体的替代转录本,以及一些非编码蛋白质的变异体。[由RefSeq,2012年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
17
8
106598 bp
58.02
23
2
8
15

IKZF3 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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