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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ikzf1 - IKAROS family zinc finger 1
Alias:
LyF-1
hlk-1
Ikaros
Zfpn1a1
Znfn1a1
mKIAA4227
5832432G11Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质属于转录因子家族,其特点是N端有一组四个DNA结合锌指和两个参与蛋白质二聚化的C端锌指。它受到表观遗传和转录因子的共同调节。这个蛋白质是造血细胞发育和稳态的转录调节因子。此外,在胚胎发育过程中,它需要赋予视网膜祖细胞临时分化能力,证明在神经系统发育中具有基本功能。可变剪接导致多个转录变异体,编码不同的异构体。[RefSeq,2014年9月提供]
Related ID:
NCBI:22778
ENSEMBL:ENSMUSG00000018654
UNIPROT:Q03267
Basic Information
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Length
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22778
88
9
87961 bp
Unknown
19
9
Ikzf1 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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