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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Zic2 - zinc finger protein of the cerebellum 2
Alias:
Ku
HPE5
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II顺式调控区域序列特异性DNA结合活性;以及染色质DNA结合活性。参与转录调控,DNA模板化;视网膜神经节细胞轴突引导;以及视觉感知。在多个过程的上游或内部发挥作用,包括纤毛组织;神经系统发育;以及正调控节点信号通路,涉及侧中部左/右不对称性决定。位于细胞质和核中。在多个结构中表达,包括消化系统;大脑;胚胎间充质;眼睛;以及神经外胚层。用于研究全前脑无裂5和精神分裂症。该基因的人类同源物与全前脑无裂和全前脑无裂5有关。与人类ZIC2(Zic家族成员2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:22772
ENSEMBL:ENSMUSG00000061524
UNIPROT:Q62520
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22772
1
3
4945 bp
Unknown
13
1
Zic2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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