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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Zic1 - zinc finger protein of the cerebellum 1
Alias:
ZIC
ZNF201
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性结合RNA聚合酶II和RNA聚合酶II的顺式调控区域序列。参与多个过程,包括中枢神经系统发育;蛋白质导入核内的正向调节;以及平滑化信号通路调控。在成年行走行为和中枢神经系统发育的上游或内部发挥作用。位于细胞质和细胞核中。在多个结构中表达,包括中枢神经系统;胚胎间充质;未来大脑;肾单位;和视觉系统。用于研究Dandy-Walker综合征和Joubert综合征。该基因的人类同源物与Dandy-Walker综合征和颅骨早合有关。与人类ZIC1(Zic家族成员1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:22771
ENSEMBL:ENSMUSG00000032368
UNIPROT:P46684
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22771
3
3
10026 bp
48.33
5
9
Zic1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
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