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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Sohlh1 - spermatogenesis and oogenesis specific basic helix-loop-helix 1
Alias:
Gm110
Nohlh
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II转录调控区序列特异性DNA结合活性;以及蛋白质二聚化活性。参与卵母细胞分化;RNA聚合酶II正向调控转录;以及精子发生。在卵原细胞发生、卵巢卵泡发育和正向调控转录(基于DNA模板)的上游发挥作用。位于细胞质和细胞核中。在性腺和后肢长骨中表达。该基因的人类同源物与卵巢发育不良5和精子发生失败32有关。与人类SOHLH1(精子发生和卵发生特异性的基础螺旋-环-螺旋1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:227631
ENSEMBL:ENSMUSG00000059625
UNIPROT:Q6IUP1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
227631
4
8
4341 bp
38.19
4
7
Sohlh1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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