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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Zfp59 - zinc finger protein 59
Alias:
Mfg2
Mfg-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
克雷贝尔关联盒(KRAB)是一个约75个氨基酸的域,位于约三分之一的真核克雷贝尔型C2H2锌指蛋白(ZFPs)的N端部分。当通过DNA结合结构域连接到模板DNA上时,KRAB结构域起转录抑制子作用。尽管KRAB-ZFP的功能大多未知,但它们似乎在细胞分化和发育过程中发挥重要作用。该基因编码一个属于C2H2型锌指蛋白克雷贝尔家族的蛋白质,并与核基质结合,显示在成熟精子的核中积累。[RefSeq,2008年7月提供]
Related ID:
NCBI:22717
ENSEMBL:ENSMUSG00000078779
UNIPROT:P16373
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22717
4
5
20748 bp
74.86
2
4
Zfp59 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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