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中文人类
FGR - FGR Proto-oncogene, Src Family Tyrosine Kinase
Alias:
SRC2
c-fgr
c-src2
p55-Fgr
p58-Fgr
p55c-fgr
p58c-fgr
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这个基因是Src家族酪氨酸激酶(PTKs)的成员。编码的蛋白质包含N端的甲基化和棕榈酰化位点，一个PTK域，以及SH2和SH3域，这些域参与介导与磷酸酪氨酸和富含脯氨酸的模式的蛋白质-蛋白质相互作用。该蛋白质定位在细胞膜皱褶中，并作为β-2整合素信号传导途径触发的细胞迁移和粘附的负调节因子。感染Epstein-Barr病毒会导致该基因的过表达。已经鉴定出多种可变剪接变体，编码相同的蛋白质。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FGR Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
