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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Glis3 - GLIS family zinc finger 3
Alias:
4833409N03Rik
E330013K21Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是GLI相似锌指蛋白家族的成员,编码一个含有多个C2H2型锌指结构域的核蛋白。这个蛋白既可作为转录抑制因子,也可作为转录激活因子,并特异性地参与胰岛素转录调节。它被认为通过结合GLI-RE共识序列(GACCACCCAC)增强GLI-RE依赖的转录。人类中类似基因的突变与新生儿糖尿病和先天性甲状腺功能减退症(NDH)有关。已经识别出可变剪接的转录本变异体。[由RefSeq,2015年3月提供]
Related ID:
NCBI:226075
ENSEMBL:ENSMUSG00000052942
UNIPROT:Q6XP49
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
226075
7
11
421434 bp
83.88
7
4
Glis3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Acting
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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