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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Xrcc1 - X-ray repair complementing defective repair in Chinese hamster cells 1
Alias:
Xrcc-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
有助于3'突出端单链DNA核酸酶活性。参与几个过程,包括DNA代谢过程;蛋白质ADP核糖基化的负调控;以及DNA损伤刺激的响应调控。在DNA修复和海马发育的上游发挥作用。位于染色体端粒区域。是ERCC4-ERCC1复合物的一部分。在包括消化系统;大脑;生殖泌尿系统;血淋巴样系统腺体;肝脏和胆道系统在内的几个结构中表达。这个基因的人类同源物涉及几种疾病,包括常染色体隐性脊髓小脑性共济失调26;癌(多种);血液癌症(多种);甲型肝炎;和生殖器官癌症(多种)。与人类XRCC1(X射线修复互补组1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:22594
ENSEMBL:ENSMUSG00000051768
UNIPROT:Q60596
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22594
4
18
26740 bp
68.97
4
13
Xrcc1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
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References Literature
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