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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ercc5 - excision repair cross-complementing rodent repair deficiency, complementation group 5
Alias:
Xpg
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合活性;RNA聚合酶II复合物结合活性;和蛋白质同二聚化活性。在紫外线保护、成人寿命决定和核苷酸切除修复的上游或内部发挥作用。预测位于染色体上。预测是DNA复制因子A复合物和核苷酸切除修复复合物的一部分。预测在细胞核中活性。在中枢神经系统、生殖泌尿系统和视网膜中表达。用于研究G色皮症群的研究。这个基因的人类同源物与脑眼面骨骼综合征3、黑素瘤和G色皮症群有关。与人类ERCC5(ERCC切除修复5,核酸内切酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:22592
ENSEMBL:ENSMUSG00000026048
UNIPROT:P35689
Basic Information
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Length
MW (kDa)
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22592
4
15
36337 bp
Unknown
10
9
Ercc5 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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