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中文小鼠
Xpc - xeroderma pigmentosum, complementation group C
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激活RNA聚合酶II特异性的DNA结合转录因子结合活性，并损伤DNA结合活性。参与UV损伤切除修复。在有丝分裂内S期DNA损伤检查点信号传导的上游或内进行作用；核苷酸切除修复中的嘧啶二聚体修复；以及对UV的响应。位于细胞核和DNA损伤部位。用于研究肺癌和C组色素性皮肤萎缩。该基因的人类同源物与胰腺癌、浆液性囊腺癌、色素性皮肤萎缩和C组色素性皮肤萎缩有关。与人类XPC(XPC复合物亚基，DNA损伤识别和修复因子)正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Xpc Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
