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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
FGF10 - Fibroblast Growth Factor 10
Alias:
LADD3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。FGF家族成员具有广泛的促有丝分裂和细胞生存活性,并参与各种生物过程,包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。这种蛋白质对角质化表皮细胞具有促有丝分裂活性,但对成纤维细胞基本上没有活性,这与FGF7的生物活性相似。研究小鼠的同源物表明,这个基因是胚胎表皮形态发生所必需的,包括大脑发育、肺形态发生和Lim芽形成的启动。这个基因也被认为是在伤口愈合过程中的一级因素。[由RefSeq,2008年7月提供]
Related ID:
NCBI:2255
ENSEMBL:ENSG00000070193
HGNC:3666
UNIPROT:O15520
OMIM:602115
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2255
2
3
89174 bp
23.44
66
7
16
9
FGF10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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