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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
FGF9 - Fibroblast Growth Factor 9
Alias:
GAF
FGF-9
SYNS3
HBFG-9
HBGF-9
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。FGF家族成员具有广泛的促有丝分裂和细胞生存活性,并参与各种生物过程,包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。这种蛋白质被分离出来作为一种对培养的神经胶质细胞具有生长刺激作用的分泌因子。在神经系统中,这种蛋白质主要由神经元产生,可能对胶质细胞发育非常重要。研究发现,这个基因的鼠同源物的表达依赖于Sonic hedgehog (Shh)信号。缺乏同源基因的小鼠表现出雄性向雌性性逆转表型,这表明它在睾丸胚胎发育中发挥作用。[由RefSeq,2008年7月提供]
Related ID:
NCBI:2254
ENSEMBL:ENSG00000102678
HGNC:3687
UNIPROT:P31371
OMIM:600921
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2254
2
3
33426 bp
23.44
142
2
13
11
FGF9 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Score
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No data available
Transcripts & Proteins
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Transcript
Length(nt)
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No data available
* This data comes from NCBI.
Gene Expression
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Name
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Status
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Link
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References Literature
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