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中文人类
FGF4 - Fibroblast Growth Factor 4
Alias:
HST
KFGF
FGF-4
HST-1
HSTF1
K-FGF
HBGF-4
HSTF-1
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这个基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。FGF家族成员具有广泛的促有丝分裂和细胞生存活性，并参与各种生物过程，包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。这个基因是通过其致癌转化活性被识别的。这个基因和另一个致癌生长因子FGF3紧密位于染色体11上。在各种类型的人类肿瘤中发现了这两个基因的共同扩增。对小鼠同源物的研究提示，通过音速刺猬(SHH)信号通路在骨骼形态发生和肢芽发育中具有功能。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FGF4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
