人类

FGF3 - Fibroblast Growth Factor 3

Alias:
INT2
HBGF-3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。FGF家族成员具有广泛的促有丝分裂和细胞生存活性,并参与各种生物过程,包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。这个基因是通过与小鼠fgf3/int-2的相似性被识别出来的,这是一个在原病毒诱导的小鼠乳腺肿瘤中激活的原癌基因。人类肿瘤中这个基因的扩增频率很高,这可能对肿瘤转化和肿瘤进展非常重要。通过研究小鼠和鸡的相似基因,揭示了其在内耳形成中的作用。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
3
9449 bp
26.89
95
3
13
7

FGF3 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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