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中文人类
FGF2 - Fibroblast Growth Factor 2
Alias:
BFGF
FGFB
FGF-2
HBGF-2
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这个基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。FGF家族成员与肝素结合，具有广泛的促有丝分裂和血管生成活性。这个蛋白质与多种生物过程有关，如肢体和神经系统发育、伤口愈合和肿瘤生长。这个基因的mRNA含有多个聚腺苷酸化位点，并且可以从非AUG(CUG)和AUG起始密码子选择性地翻译，产生具有不同特性的五个不同的异构体。CUG起始的异构体位于核内，负责内源性效应，而AUG起始的形式主要是胞质性的，负责这个FGF的旁分泌和自分泌效应。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FGF2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
