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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
FGF1 - Fibroblast Growth Factor 1
Alias:
AFGF
ECGF
FGFA
ECGFA
ECGFB
FGF-1
HBGF1
HBGF-1
GLIO703
ECGF-beta
FGF-alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。FGF家族成员具有广泛的促有丝分裂和细胞生存活性,并参与各种生物过程,包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。这个蛋白质作为内皮细胞迁移和增殖的调节因子,同时也作为血管生成因子。它在体外作为各种中胚层和神经外胚层来源的细胞的促有丝分裂剂,因此被认为参与器官发生。已经描述了多种可变剪接变异体,编码不同的异构体。[由RefSeq,2009年1月提供]
Related ID:
NCBI:2246
ENSEMBL:ENSG00000113578
HGNC:3665
UNIPROT:P05230
OMIM:131220
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2246
27
4
105893 bp
17.46
7
--
3
42
FGF1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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