小鼠

Nox3 - NADPH oxidase 3

Alias:
het
GP91-3
nmf250
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码NOX家族NADPH氧化酶成员。这些酶催化电子从NADPH转移到分子氧,产生超氧化物和其他活性氧物质(ROS)。家族成员产生的ROS与许多生物学功能有关,包括宿主防御、蛋白质的翻译后处理、细胞信号传导、基因表达调节和细胞分化。这个基因编码的蛋白质主要在内耳表达,并涉及耳石的生物生成,耳石是内耳中参与感知重力和线性加速度的结晶结构。在鼠中,这个基因的突变导致耳石的缺失和前庭功能紊乱。[RefSeq,2013年6月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
13
61022 bp
64.50
10
4

Nox3 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
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Cell-specific RNA expression

Organ
Abundance
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Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

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PMID
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Year
IF
No Data Found!
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