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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Nox3 - NADPH oxidase 3
Alias:
het
GP91-3
nmf250
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码NOX家族NADPH氧化酶成员。这些酶催化电子从NADPH转移到分子氧,产生超氧化物和其他活性氧物质(ROS)。家族成员产生的ROS与许多生物学功能有关,包括宿主防御、蛋白质的翻译后处理、细胞信号传导、基因表达调节和细胞分化。这个基因编码的蛋白质主要在内耳表达,并涉及耳石的生物生成,耳石是内耳中参与感知重力和线性加速度的结晶结构。在鼠中,这个基因的突变导致耳石的缺失和前庭功能紊乱。[RefSeq,2013年6月提供]
Related ID:
NCBI:224480
ENSEMBL:ENSMUSG00000023802
UNIPROT:Q672J9
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
224480
1
13
61022 bp
64.50
10
4
Nox3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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