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中文小鼠
Wrn - Werner syndrome RecQ like helicase
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具有3'-5'核酸酶活性。参与G-四联体DNA解旋。在几个过程的上游或内部发挥作用，包括多细胞生物衰老；生长速度的调节；和复制性衰老。位于染色体，端区；核质；和复制叉。在睾丸的体腔上皮、肾单位和脾脏中表达。用于研究Werner综合征。这个基因的人类同源物与Werner综合征、乳腺癌、冠状动脉疾病（多种）、弥漫性硬皮病和老年性白内障有关。与人类的WRN（RecQ样解旋酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Wrn Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
