Wnt7a - wingless-type MMTV integration site family, member 7A

Enables frizzled binding activity. Involved in several processes, including dendritic spine morphogenesis; modulation of chemical synaptic transmission; and reproductive structure development. Acts upstream of or within several processes, including animal organ development; blood vessel morphogenesis; and embryonic limb morphogenesis. Located in cell surface; extracellular matrix; and glutamatergic synapse. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; brain; embryo ectoderm; reproductive system; and sensory organ. Used to study Fuhrmann syndrome. Human ortholog(s) of this gene implicated in Fuhrmann syndrome and Schinzel type phocomelia. Orthologous to human WNT7A (Wnt family member 7A). [provided by Alliance of Genome Resources, Apr 2022]