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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Adamts20 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Alias:
bt
Adamst20
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于“去整合素和金属蛋白酶含血栓素主题模式”(ADAMTS)家族的多结构域基质相关金属内肽酶,在组织形态发生和病理生理重塑、炎症和血管生物学中具有多种作用。编码的前原原蛋白经历蛋白水解加工以产生活性蛋白酶。这个基因中的一些特定突变导致神经嵴来源的黑色素细胞发育缺陷,从而导致腰部区域出现白色斑点的“带状”表型。[RefSeq,2016年7月提供]
Related ID:
NCBI:223838
ENSEMBL:ENSMUSG00000022449
UNIPROT:P59511
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
223838
6
39
163790 bp
212.07
27
9
Adamts20 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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Name
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