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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mrtfa - myocardin related transcription factor A
Alias:
Mal
AMKL
Bsac
Mkl1
Mrtf-A
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个具有多种功能的蛋白质,包括DNA结合转录因子活性,肌动蛋白单体结合活性和转录共激活活性。该蛋白质参与肌动蛋白细胞骨架的组织以及通过血清响应元素结合活性正向调节转录。它还在细胞凋亡过程的负向调节中起到上游或内部作用,以及通过RNA聚合酶II正向调节转录。该蛋白质位于细胞质和细胞核中,在小脑、早期概念期、肝脏、卵母细胞和端脑中表达。这个基因的人类同源物与急性巨核细胞白血病和免疫缺陷66有关。该蛋白质与人类MRTFA(心肌蛋白相关转录因子A)同源。
Related ID:
NCBI:223701
ENSEMBL:ENSMUSG00000042292
UNIPROT:Q8K4J6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
223701
2
14
178456 bp
102.55
4
14
Mrtfa Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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References Literature
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