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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ulk1 - unc-51 like kinase 1
Alias:
Unc51.1
mKIAA0722
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活Hsp90蛋白结合活性;蛋白激酶结合活性;和蛋白丝氨酸/苏氨酸激酶活性。参与几个过程,包括细胞对氨基酸饥饿的反应;宏自噬;和对线粒体去极化的反应。在几个过程的上游或内部发挥作用,包括神经系统发育;蛋白自磷酸化;和神经生长因子TRK受体信号通路调控。位于几个细胞成分中,包括胞质囊泡膜;神经元细胞体;和吞噬泡组装位点膜。是Atg1/ULK1激酶复合物的一部分。在几个结构中表达,包括中枢神经系统和视网膜。与人类的ULK1(类似于unc-51的自噬激活激酶1)正链同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:22241
ENSEMBL:ENSMUSG00000029512
UNIPROT:O70405
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22241
5
28
25637 bp
112.46
9
12
Ulk1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
Strain of Origin
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No data available
References Literature
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IF
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