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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ubb - ubiquitin B
Alias:
Ubc
Ubb2
Uba52
Rps27a
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码泛素,是一种最保守的已知蛋白质。泛素在将细胞内蛋白质靶向为被26S蛋白酶体降解方面具有重要作用。它还参与染色质结构的维护、基因表达的调节和应激反应。泛素作为前体蛋白质合成,由聚泛素链或一个与无关蛋白质融合的单个泛素部分组成。这个基因由四个直接重复的泛素编码序列组成,没有间隔序列。因此,该蛋白质作为具有最后一个重复后的最终氨基酸的聚泛素前体表达。这个基因的假基因位于染色体3和14上。可变剪接导致多个转录变异体。[RefSeq,2015年9月提供]
Related ID:
NCBI:22187
ENSEMBL:ENSMUSG00000019505
UNIPROT:P0CG49
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22187
2
2
1709 bp
34.37
3
10
Ubb Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Name
MGI
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