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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tyms - thymidylate synthase
Alias:
Ts
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种酶,该酶使用5,10-亚甲基四氢叶酸作为辅因子,催化脱氧尿苷酸甲基化为脱氧胸苷酸。这个功能维持了胸苷-5'-单磷酸盐的浓度,这对于DNA复制和修复至关重要。编码的酶是癌症化疗药物的目标。这个基因的大部分转录本缺乏3'UTR(PMID: 3022294,3444407)。这些转录本的终止密码子是UAA,与在基因组和更长转录本中发现的UAG不同,因为polyA位点位于终止密码子内(PMID: 3444407,2157203)。一个相关的假基因已经在染色体10上被鉴定。[由RefSeq,2010年3月提供]
Related ID:
NCBI:22171
ENSEMBL:ENSMUSG00000025747
UNIPROT:P07607
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22171
3
7
35718 bp
34.96
4
10
Tyms Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
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* This data comes from NCBI.
Gene Expression
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Name
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