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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CES5A - Carboxylesterase 5A
Alias:
CES5
CES7
CAUXIN
CES4C1
HEL126
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码羧酸酯酶大家族的一员。这个家族的成员负责水解或转移各种外源性物质,如可卡因和海洛因,以及具有酯、硫酯或酰胺键的内源性底物。它们还参与脂肪酸和胆固醇酯的代谢,可能参与血脑屏障系统。这个基因,也被称为CES5,主要在外周组织中表达,包括大脑、肾脏、肺和睾丸。它编码一种分泌酶。由于在雄性家猫的尿液中高水平存在,这种酶也被称为cauxin(羧酸酯酶样尿排泄蛋白)。这种酶在调节信息素前体的产生中发挥作用,并可能参与男性生殖液中的脂质和胆固醇转移过程。已经发现这个基因的多个转录变异体,编码不同的异构体。[由RefSeq,2010年6月提供]
Related ID:
NCBI:221223
ENSEMBL:ENSG00000159398
HGNC:26459
UNIPROT:Q6NT32
OMIM:618678
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
221223
3
13
109878 bp
63.93
25
--
4
3
CES5A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
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No data available
Transcripts & Proteins
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Transcript
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CDS(bp)
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No data available
* This data comes from NCBI.
Gene Expression
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Alphabetical
Cell-specific RNA expression
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Type
Name
MGI
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CAS Number
Status
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Link
No data available
References Literature
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