人类

MARCHF8 - Membrane Associated Ring-CH-type Finger 8

Alias:
MIR
CMIR
c-MIR
MARCH8
RNF178
MARCH-VIII
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
MARCH8是膜结合E3泛素连接酶MARCH家族的一员(EC 6.3.2.19)。MARCH酶将泛素添加到底物蛋白质的靶定赖氨酸上,从而信号传递其在内质网膜间室中的运输。MARCH8诱导几种膜糖蛋白的内化(Goto等人,2003年[PubMed 12582153];Bartee等人,2004年[PubMed 14722266])。由OMIM于2010年4月提供。

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
14
8
140323 bp
32.97
--
--
6
16

MARCHF8 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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