Trpc3 - transient receptor potential cation channel, subfamily C, member 3

Predicted to enable calcium activated cation channel activity; inositol 1,4,5 trisphosphate binding activity; and store-operated calcium channel activity. Predicted to be involved in several processes, including metal ion transport; positive regulation of cardiac muscle hypertrophy in response to stress; and response to ATP. Predicted to act upstream of or within calcium ion transport. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. Is expressed in cochlea; ganglia; limb; spinal cord; and trunk somite. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]