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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Trf - transferrin
Alias:
HP
Tf
Tfn
hpx
Cd176
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
铁分子伴侣活性预测;铁离子结合活性;转铁蛋白受体结合活性。参与几个过程,包括ERK1和ERK2级联反应;破骨细胞分化;和骨吸收的正调控。在SMAD蛋白信号传导、铁离子运输和细菌反应的上游或内部发挥作用。位于clathrin包被的坑和细胞质囊泡中。在几个结构中表达,包括大脑、肝脏、胎盘、白色脂肪和黄囊。用于研究先天性转铁蛋白血症。该基因的人类同源物与贫血、先天性转铁蛋白血症、葡萄糖代谢疾病(多种)、铁缺乏性贫血和不安腿综合症有关。与人类TF(转铁蛋白)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:22041
ENSEMBL:ENSMUSG00000032554
UNIPROT:Q921I1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
22041
1
17
21411 bp
76.72
8
9
Trf Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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Name
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