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Trex1 - three prime repair exonuclease 1

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合活性;WW结构域结合活性;和镁离子结合活性。参与DNA代谢过程。在几个过程的上游或内部发挥作用,包括DNA代谢过程;细胞对细胞因子刺激的响应;和前体代谢物和能量产生的调节。位于细胞质;内质网;和核复制叉。是寡糖基转移酶复合物和蛋白质-DNA复合物的一部分。用于研究Aicardi-Goutieres综合征和皮肤狼疮红斑。这个基因的人类同源物涉及Aicardi-Goutieres综合征;寒战狼疮;视网膜血管病变伴脑白质营养不良;和系统性红斑狼疮。与人类TREX1(三个修复核酸酶1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
2
1792 bp
33.67
17
16

Trex1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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