小鼠

Tph1 - tryptophan hydroxylase 1

Alias:
Tph
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个依赖生物素的芳香族氨基酸羟化酶家族的成员。编码的蛋白质是两种催化血清素生物合成中的第一个和限速步骤的色氨酸羟化酶之一。这个基因在外周器官中表达,而色氨酸羟化酶2在神经元中表达。编码的蛋白质参与低氧诱导的肺压力和肺血管重构升高的发展,并被认为是一种免疫耐受调节剂。这个基因的破坏与心脏功能紊乱有关。选择性剪接导致多个转录变异体。[RefSeq,2013年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
11
27897 bp
51.34
12
10

Tph1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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