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中文小鼠
Top3a - topoisomerase (DNA) III alpha
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预测能够激活DNA拓扑异构酶I型(单链切割，ATP非依赖型)活性和单链DNA结合活性。预测参与DNA拓扑变化；染色体分离；和线粒体DNA代谢过程。预测位于PML体中。预测在细胞核中活性。在几个结构中表达，包括肾上腺；心血管系统；生殖泌尿系统；肠道；和神经系统。这个基因的人类正显子(s)与常染色体隐性进行性外展眼肌麻痹有关，伴有线粒体DNA缺失5。与人类TOP3A(DNA拓扑异构酶IIIα)正显子同源。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Top3a Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
