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中文人类
FAP - Fibroblast Activation Protein Alpha
Alias:
FAPA
SIMP
DPPIV
FAPalpha
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这个基因编码的蛋白质是一种同型二聚体整合膜明胶酶，属于丝氨酸蛋白酶家族。它选择性地在上皮癌的反应性基质成纤维细胞、愈合伤口的肉芽组织以及骨和软组织肉瘤的恶性细胞中表达。这个蛋白质被认为涉及在发育、组织修复和上皮癌发生过程中对成纤维细胞生长或上皮-间充质相互作用的控制。已经发现这个基因有不同的剪接转录变异体，它们编码不同的异构体。[由RefSeq，2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
FAP Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
