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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Wapl - WAPL cohesin release factor
Alias:
FOE
DIF-2
Wapal
A530089A20Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质对cohesin从染色质中释放很重要。这个基因产物被认为对发育是必需的,而细胞中这个基因表达减少会导致染色质结构缺陷。这个基因的人源同源物在宫颈癌中高表达,而小鼠中这个基因的人源同源物的表达会导致肿瘤形成。可变剪接产生多种编码不同蛋白质异型的转录变异体。[RefSeq,2014年8月提供]
Related ID:
NCBI:218914
ENSEMBL:ENSMUSG00000041408
UNIPROT:Q65Z40
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
218914
3
19
75855 bp
134.07
6
9
Wapl Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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