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中文小鼠
Timeless - timeless circadian clock 1
Alias:
tim
Debt69
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这个基因编码的蛋白质高度保守，参与损伤或应激后的细胞生存，DNA聚合酶ε活性的增加，端粒长度的维持，以及上皮细胞形态发生。编码的蛋白质还在昼夜节律自调循环中发挥作用，与PERIOD基因（PER1、PER2和PER3）以及其他基因相互作用，通过CLOCK/ARNTL下调PER1的激活。这个基因或其表达的改变可能促进前列腺癌、肺癌、乳腺癌和精神障碍的发生。已发现这个基因有几个编码不同异型的转录变异体。[RefSeq，2014年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Timeless Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
