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Trim24 - tripartite motif-containing 24

Alias:
TIF1
Tif1a
TIF1alpha
TIF1-alpha
A130082H20Rik
D430004I05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是三重模式域含有家族(TRIM)的一部分,该家族以RING、B-box类型1、B-box类型2和螺旋-螺旋区域结构域为特征。这种蛋白质还含有PHD/TTC指型和bromodomain,对调节核受体和结合染色质非常重要,在分化、发展和组织内稳态中具有重要作用。这种蛋白质已报道可以调节肿瘤抑制因子p53和视黄酸受体的活性。这个基因与Braf转化基因之间的易位事件已经报道在肝细胞癌中,导致融合蛋白T18。可变剪接产生了多种编码不同蛋白质异型的转录变异体。[RefSeq,2013年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
19
98565 bp
116.66
9
22

Trim24 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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