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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Thrb - thyroid hormone receptor beta
Alias:
Nr1a2
Thrb1
Thrb2
T3R[b]
T3Rbeta
c-erbAbeta
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活染色质DNA结合活性及核受体活性。在几个过程的上游或内部发挥作用,包括雌性交配行为;RNA聚合酶II的转录调节;以及视网膜锥细胞凋亡过程。位于细胞核中。在几个结构中表达,包括棕色脂肪;内分泌腺;肝脏;感觉器官;前庭蜗神经节。用于研究注意力缺陷多动障碍;甲状腺滤泡癌;以及甲状腺激素抵抗综合症。这个基因的人类同源物与几种疾病有关,包括乳腺癌(多种);子宫颈原位癌;肾细胞癌;选择性垂体甲状腺激素抵抗;以及甲状腺激素抵抗综合症。与人类THRB(甲状腺激素受体β)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:21834
ENSEMBL:ENSMUSG00000021779
UNIPROT:P37242
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
21834
21
7
380940 bp
52.63
23
11
Thrb Genetics information (-)
GRCm39
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* This data comes from NCBI.
Gene Expression
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