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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Kdm1b - lysine (K)-specific demethylase 1B
Alias:
Aof1
4632428N09Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有黄素腺嘌呤二核苷酸结合活性;组蛋白H3-di/monomethyl-lysine-4依赖FAD的脱甲基酶活性;和锌离子结合活性。参与DNA甲基化的调节。在精子发生、组蛋白H3-K4脱甲基化和遗传印记调控基因表达的上游或DNA甲基化内发挥作用。位于细胞核中。在包括消化系统、泌尿生殖系统、皮肤系统、神经系统和感觉器官在内的几个结构中表达。与人类的KDM1B(赖氨酸脱甲基酶1B)正同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:218214
ENSEMBL:ENSMUSG00000038080
UNIPROT:Q8CIG3
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
218214
8
22
41237 bp
92.63
5
5
Kdm1b Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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