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中文小鼠
Tgfbr1 - transforming growth factor, beta receptor I
Alias:
ALK5
ESK2
Alk-5
TGFR-1
TbetaRI
TbetaR-I
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这个基因编码一种转化生长因子β(TGF-β)受体家族蛋白质的成员。这些蛋白质构成了TGF-β信号通路的一个组成部分，该通路将细胞外的信号转导为基因表达变化，以调节广泛的细胞反应，包括增殖、迁移、分化和凋亡。这个基因的纯合子敲除小鼠表现出血管生成受损和胚胎致死。可变剪接导致多个转录变异体。[RefSeq,2015年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Tgfbr1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
