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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Serpina10 - serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
Alias:
PZI
ZPI
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是大丝氨酸蛋白酶家族的一员,也被称为依赖PZ的丝氨酸蛋白酶抑制剂(ZPI或PZI)。这个蛋白质被认为在凝血调节中扮演重要角色。它直接抑制因子XIa,并且在有钙、磷脂和蛋白Z(PZ)存在时,还可以抑制因子Xa。这个基因的缺陷导致血栓形成增加。可选的剪接产生了多个编码多种蛋白质异型的转录变异体。[由RefSeq,2014年8月提供]
Related ID:
NCBI:217847
ENSEMBL:ENSMUSG00000061947
UNIPROT:Q8R121
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
217847
2
5
14748 bp
51.80
5
6
Serpina10 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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