Acts upstream of or within several processes, including chordate embryonic development; hematopoietic stem cell homeostasis; and regulation of signal transduction. Located in nucleolus. Is expressed in several structures, including 2-cell stage embryo; gonad; hemolymphoid system gland; inner cell mass; and liver. Orthologous to human NLE1 (notchless homolog 1). [provided by Alliance of Genome Resources, Apr 2022]