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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tek - TEK receptor tyrosine kinase
Alias:
Hyk
STK1
Tie2
Tie-2
Cd202b
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活蛋白质酪氨酸激酶活性和信号受体活性。参与几个过程,包括循环系统发育;负调控内皮细胞凋亡过程;以及响应视黄酸。在几个过程的上游或内部发挥作用,包括大分子代谢过程的正向调控;蛋白质导入核内的正向调控;以及NIK/NF-kappaB信号传导的调控。位于细胞质核周区域。在几个结构中表达,包括心血管系统;中枢神经系统;胚外成分;生殖泌尿系统;以及血淋巴样系统腺体。该基因的人类同源物与动脉静脉畸形和多部位皮肤和粘膜静脉畸形有关。与人类TEK(TEK受体酪氨酸激酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:21687
ENSEMBL:ENSMUSG00000006386
UNIPROT:Q02858
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
21687
4
23
135892 bp
125.70
16
23
Tek Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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References Literature
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IF
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