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中文小鼠
Cgas - cyclic GMP-AMP synthase
Alias:
Mb21d1
E330016A19Rik
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这个基因编码的蛋白质是一种在细胞质中结合DNA的核蛋白，在感知细胞质中DNA的存在后，催化环状鸟苷酸单磷酸-腺苷酸单磷酸（cGAMP）的合成。cGAMP结合另一种蛋白质，干扰素基因刺激剂（STING），导致干扰素的诱导和宿主免疫反应。这个基因表达减少会抑制某些病毒感染情况下干扰素的诱导。可变剪接产生多个转录变异体。[RefSeq，2014年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Cgas Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
