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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tfap2a - transcription factor AP-2, alpha
Alias:
Ap2
AP-2
Ap2tf
Tcfap2a
AP2alpha
Ap-2 (a)
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是激活蛋白2(AP-2)转录因子家族的成员。这个基因编码的蛋白质可以同时作为基因转录的激活子和抑制子,在早期胚胎发育中起着重要作用,特别是在颅面部发育中。这个蛋白质可以形成同源二聚体和异源二聚体,并结合到某些启动子和增强子中的GC丰富共识序列。这个基因的破坏导致围产期死亡,伴有神经管、颅面部和肢体中胚层缺陷。选择性剪接产生了多个转录变异体,它们编码多种蛋白质异构体。[RefSeq, 2014年9月提供]
Related ID:
NCBI:21418
ENSEMBL:ENSMUSG00000021359
UNIPROT:P34056
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
21418
7
7
24438 bp
47.97
10
14
Tfap2a Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Type
Name
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