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Tfap2a - transcription factor AP-2, alpha

Alias:
Ap2
AP-2
Ap2tf
Tcfap2a
AP2alpha
Ap-2 (a)
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是激活蛋白2(AP-2)转录因子家族的成员。这个基因编码的蛋白质可以同时作为基因转录的激活子和抑制子,在早期胚胎发育中起着重要作用,特别是在颅面部发育中。这个蛋白质可以形成同源二聚体和异源二聚体,并结合到某些启动子和增强子中的GC丰富共识序列。这个基因的破坏导致围产期死亡,伴有神经管、颅面部和肢体中胚层缺陷。选择性剪接产生了多个转录变异体,它们编码多种蛋白质异构体。[RefSeq, 2014年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
7
7
24438 bp
47.97
10
14

Tfap2a Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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