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Tcf4 - transcription factor 4

Alias:
ME2
TFE
E2-2
E2.2
ITF2
SEF2
ITF-2
SEF-2
Tcf-4
ASP-I2
ITF-2b
SEF2-1
MITF-2A
MITF-2B
bHLHb19
5730422P05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个具有多种功能的蛋白质,包括DNA结合转录激活活性,RNA聚合酶II特异性;E-box结合活性;和TFIIB类转录因子结合活性。该基因参与神经元分化的正调控,RNA聚合酶II转录的正调控,以及蛋白质-DNA复合物的组装。该基因位于核内,是转录调节复合物的一部分。该基因在包括消化系统、大脑、生殖系统和呼吸系统在内的多个结构中表达。该基因用于研究Pitt-Hopkins综合征和精神分裂症。该基因的人类同源物与Fuchs内皮营养不良和Pitt-Hopkins综合征有关。该基因与人类TCF4(转录因子4)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
48
20
344539 bp
71.62
10
15

Tcf4 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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