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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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小鼠
Tcf4 - transcription factor 4
Alias:
ME2
TFE
E2-2
E2.2
ITF2
SEF2
ITF-2
SEF-2
Tcf-4
ASP-I2
ITF-2b
SEF2-1
MITF-2A
MITF-2B
bHLHb19
5730422P05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个具有多种功能的蛋白质,包括DNA结合转录激活活性,RNA聚合酶II特异性;E-box结合活性;和TFIIB类转录因子结合活性。该基因参与神经元分化的正调控,RNA聚合酶II转录的正调控,以及蛋白质-DNA复合物的组装。该基因位于核内,是转录调节复合物的一部分。该基因在包括消化系统、大脑、生殖系统和呼吸系统在内的多个结构中表达。该基因用于研究Pitt-Hopkins综合征和精神分裂症。该基因的人类同源物与Fuchs内皮营养不良和Pitt-Hopkins综合征有关。该基因与人类TCF4(转录因子4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:21413
ENSEMBL:ENSMUSG00000053477
UNIPROT:Q60722
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
21413
48
20
344539 bp
71.62
10
15
Tcf4 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Type
Name
MGI
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IF
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