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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tap2 - transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Alias:
Y1
jas
APT2
Ham2
MTP2
PSF2
ABC18
Abcb3
Ham-2
Tap-2
RING11
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的膜关联蛋白是ATP结合盒(ABC)转运蛋白超家族的一员。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)。这个蛋白属于MDR/TAP亚家族。MDR/TAP亚家族的成员参与多重药物抗性。这个基因编码的蛋白参与抗原呈现。这个蛋白与Tap1形成异源二聚体,以将肽从细胞质运输到内质网。人类基因中的突变可能与强直性脊柱炎、胰岛素依赖性糖尿病和乳糜泻疾病有关。[由RefSeq,2008年7月提供]
Related ID:
NCBI:21355
ENSEMBL:ENSMUSG00000024339
UNIPROT:P36371
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
21355
1
12
11843 bp
77.44
7
2
Tap2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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