Lcor - ligand dependent nuclear receptor corepressor

Enables chromatin binding activity. Involved in positive regulation of histone H3-K27 trimethylation. Acts upstream of or within negative regulation of transcription by RNA polymerase II and transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including 1st branchial arch; genitourinary system; long bone epiphysis; nervous system; and sensory organ. Orthologous to human LCOR (ligand dependent nuclear receptor corepressor). [provided by Alliance of Genome Resources, Apr 2022]