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中文人类
MECOM - MDS1 And EVI1 Complex Locus
Alias:
EVI1
MDS1
KMT8E
PRDM3
RUSAT2
MDS1-EVI1
AML1-EVI-1
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这个基因编码的蛋白质是一种转录调节蛋白和癌蛋白，可能参与造血、凋亡、发育和细胞分化与增殖。编码的蛋白质可以与CTBP1、SMAD3、CREBBP、KAT2B、MAPK8和MAPK9相互作用。这个基因可以与AML1基因发生易位，导致这个基因的过度表达和白血病的发生。已经发现这个基因有几个不同转录变异体，编码几种不同的异构体。[由RefSeq，2011年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MECOM Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
