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中文人类
ESR2 - Estrogen Receptor 2
Alias:
Erb
ESRB
ODG8
ESTRB
NR3A2
ER-BETA
ESR-BETA
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这个基因编码一个雌激素受体家族的成员，属于核受体转录因子超家族。基因产物包含一个N-端DNA结合域和一个C-端配体结合域，定位于细胞核、细胞质和线粒体。在与17β-雌二醇或相关配体结合后，编码的蛋白质形成同源或异源二聚体，与特定的DNA序列相互作用以激活转录。一些异构体主要抑制其他雌激素受体家族成员的活性。已经描述了这个基因的几种可变剪接转录变异体，但其中一些变异体的完整长度尚未完全确定。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ESR2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
