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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Syk - spleen tyrosine kinase
Alias:
Sykb
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括ATP结合活性;SH2结构域结合活性;和酶结合活性。参与多个过程,包括细胞表面受体信号通路;参与免疫应答的髓细胞激活;以及调节囊泡介导的运输。在几个过程的上游或内部发挥作用,包括白细胞激活的正调控;大分子代谢过程的正调控;和蛋白质磷酸化。位于早期噬菌体中。是B细胞受体复合物的一部分。在肝脏中表达。这个基因的人类同源物与原发性免疫缺陷病有关。与人类的SYK(脾脏关联的酪氨酸激酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:20963
ENSEMBL:ENSMUSG00000021457
UNIPROT:P48025
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
20963
6
14
66159 bp
71.38
19
36
Syk Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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